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Carbohydrate Derivative

1-O-Acetyl-2,3,5-Tri-O-Benzoyl-β-D-Ribofuranose

Synonyms: Acetyltribenzoylribose; 1-acetyl-2,3,5-tribenzoyl-β-D-ribofuranose; 2,3,5-tri-O-benzoyl-1-O-acetyl-beta-D-ribofuranose; β-D-ribofuranose-1-acetate 2,3,5-tribenzoate.

Molecular Formula: C28H24O9

Molecular weight: 504.48

CAS No.: 6974-32-9

EC No.: 230-220-4

Molecular structure:

Quality Standard:

Item

Specification

Appearance

Assay (HPLC), %

Melting point, ℃

Specific rotation,(C=1,CHCl3

Loss on drying , %

Residue on igntion , %

White to off-white crystalline solid

≥98.0

127.0~133.0

+40.0~+45.0

≤0.5

≤0.1

Characteristics: The product is white or off-white crystalline solid. It is soluble in alcohol but insoluble in water.

Uses: The product is an important pharmaceutical material and intermediate. It is used in synthesis anti-tumor drugs such as Azacitidine and Selenazofurin, nucleoside antibiotics Toyocamycin, and 2-chloro-N6-methyl adenosine use as vasodilators or hypotensive and/or anticoagulant drugs, etc. It is also use in synthesis the following compounds ¢Ù The analogues of adenosine, uridine, guanosine, cytidine, purine nucleosides that possess antitumor activity, for example, thiazolo[4,5-d]/ pyrazolo[3,4 d]/ pyrido[2,3-d]/ pyrrolo[2,3-d] / or imidazo[4,5-d]pyrimidone nucleoside, thiazolecarboxamide nucleoside, phosphazole[4,5-d]pyrimidines nucleoside, halo-imidazo[4,5-c]pyridine (or imidazo[4,5-c]pyridin-4-one) nucleoside, 2- or 7-chloro(fluoro) -9-deazanosine, Clitocine and 2-fluoro- / or 7-methyl-9-deazanosine which having anti-leukemia. ¢ÚVarious antiviral and antibacterial activity compounds, for example, 5-butylpyrimidine nucleosides having anti- polio and IHD strain vaccinia virus, benzylthio purine nucleoside having anti-toxoplasma gondii virus, N3,5'-Cyclo-4-(β-D-ribosyl)-vic-triazolo[4,5-b]pyridin-5-one and its analogs having anti- flavivirus especially hepatitis C virus, thieno[2,3-d] pyrimidine nucleoside having anti-E. coli activity, isatin ribonucleosides having anti-herpes simplex virus(HSV), N-ribosyl 2- and 8-halo-4H-1,4-benzothiazine having both anti-B. subtilis and anthelmintic activity, phenothiazines nucleoside having both anti-C. albicans, coagulase negative staphylococci strain and antioxidant, 3-fluoro-10H-phenothiazines nucleosides having both anti- P. aeruginosa, E. coli, S. aureus, B. cereus and antioxidant, thieno[2,3-d]pyrimidine-thio-ribonucleosides having anti- E. coli, B. subtilis, C. albicans and A. niger, pyrido[2,3-d]pyridimines nucleosides having anti- E. coli, S. aureus, A. niger and A. flavus, ribosyl-1,2,4-triazin-6(1H)-/ones or thiones having anti- A. fumigatus, Penicillium, Syncephalastrum racemosum, C. albicans and E. coli, 6-benzylamino-2-thio-pyrimidinone nucleoside having anti-E. coli, S. aureus, C. albicans. ¢Û Deaminase inhibitor triazolo[3,4f] triazine-C-nucleoside, Toll-like receptor agonist pyrido[2,3-d] pyrimidone nucleoside, queuosine (a kind of T-RNA nucleoside), pterin ribonucleosides, deoxyriboses and its derivatives.

Storage: Maintain in cool, dry containment.

Package: 10kg/drum or as customer require.

Expiration Date: 2 years.

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0086-579-82270620

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