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CasNo: 4163-59-1
MF: C16H22O11
Synonyms:α-D-Galactose pentaacetate;Pentaacetyl-α-D-galactopyranose,;Pentaacetyl α-D-galactose;1,2,3,4,6-Penta-O-acetyl-α-D-galactopyranose
Molecular Formula: C16H22O11
Molecular Weight: 390.34
CAS No.: 4163-59-1
EC No.:609-944-3
Specification:
|
Item |
Specification |
|
Appearance |
White crystalline powder |
|
Assay(GC),% |
≥98.0 |
|
Melting Point, ℃ |
92.0~98.0 |
|
Specific rotation, |
+103.0~+107.0 |
|
Water,% |
≤1.0 |
|
Residue on ignition, % |
≤0.1 |
α-D-Galactose pentaacetate is mainly used as medicine intermediate. As follows:
1. It is used for the preparation of galactose derivative cationic liposome nanoparticles to meet basic requirements of nucleic acid drug transporters.
2. It is used for recyclable binders for metal casting molds and for injection molding of metal and ceramic parts.
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1-(4-hydroxy-3,5-dimethoxy-phenyl)-ethanone


acetic anhydride


2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide


D-glucose pentaacetate


1-(4-acetoxy-3,5-dimethoxy-phenyl)-ethanone


3,5-dimethoxy-4-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxy)acetophenone
| Conditions | Yield |
|---|---|
|
Yield given. Multistep reaction;
|

nudicauloside B


acetic anhydride


D-glucose pentaacetate


1,2,3,4-tetra-O-acetyl-L-arabinopyranose
| Conditions | Yield |
|---|---|
|
nudicauloside B; With hydrogenchloride; water; for 4h; Reflux;
With methyldioctylamine; In chloroform; water;
acetic anhydride; With pyridine; for 24h;
|

β-D-mannose

acetic anhydride

D-Mannose

D-Mannose

1-O-p-nitrophenyl-2,3,4,6-tetra-O-acetyl α-D-mannopyranoside

ethyl 2,3,4,6-tetra-O-acetyl-1-thio-β-D-mannopyranoside

S-ethyl 2,3,4,6-tetra-O-acetyl-1-deoxy-1-thio-α-D-mannopyranoside

1-O-phenyl-2,3,4,6-tetra-O-acetyl-β-D-mannopyranoside