What is the 2',3'-O-isopropylidene cytidine?

2',3'-O-isopropylidene cytidine is , while it's Molecular Formula is C12H17 N3 O5. 2'',3''-Isopropylidenecytidine is an intermediate in synthesizing 5-Hydroxymethylcytidine-13CD2 (H947092), an analogue of 5-Hydroxymethylcytidine (H947090) which is a product in DNA hydroxymethylation.

What is the CAS number for 2',3'-O-isopropylidene cytidine?

The CAS number of 2',3'-O-isopropylidene cytidine is 362-42-5.

What is 2',3'-O-isopropylidene cytidine (362-42-5) used for?

2',3'-O-isopropylidene cytidine is a chemical compound that serves as an intermediate in the synthesis of 5-Hydroxymethylcytidine-13CD2 (H947092), an analogue of 5-Hydroxymethylcytidine (H947090). This analogue is involved in the process of DNA hydroxymethylation, which is an important epigenetic modification.InChI:InChI=1/C12H17N3O5/c1-12(2)19-8-6(5-16)18-10(9(8)20-12)15-4-3-7(13)14-11(15)17/h3-4,6,8-10,16H,5H2,1-2H3,(H2,13,14,17)

What is the 2',3'-O-isopropylidene cytidine?

2',3'-O-isopropylidene cytidine is , while it's Molecular Formula is C12H17 N3 O5. 2'',3''-Isopropylidenecytidine is an intermediate in synthesizing 5-Hydroxymethylcytidine-13CD2 (H947092), an analogue of 5-Hydroxymethylcytidine (H947090) which is a product in DNA hydroxymethylation.

What is the CAS number for 2',3'-O-isopropylidene cytidine?

The CAS number of 2',3'-O-isopropylidene cytidine is 362-42-5.

What is 2',3'-O-isopropylidene cytidine (362-42-5) used for?

2',3'-O-isopropylidene cytidine is a chemical compound that serves as an intermediate in the synthesis of 5-Hydroxymethylcytidine-13CD2 (H947092), an analogue of 5-Hydroxymethylcytidine (H947090). This analogue is involved in the process of DNA hydroxymethylation, which is an important epigenetic modification.InChI:InChI=1/C12H17N3O5/c1-12(2)19-8-6(5-16)18-10(9(8)20-12)15-4-3-7(13)14-11(15)17/h3-4,6,8-10,16H,5H2,1-2H3,(H2,13,14,17)

2',3'-O-Isopropylidenecytidine

Basic information

Product Name:2',3'-O-Isopropylidenecytidine
CasNo.:362-42-5
MF:C12H17 N3 O5
MW:283.284

Physical and Chemical Properties

Boiling Point:238-240℃ (methanol )
Packing:25kg/drum or as required by customer
Throughput:

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Product Details

CasNo： 362-42-5

MF： C12H17 N3 O5

Packing： 25kg/drum or as required by customer

Reputable supplier selling 2',3'-O-Isopropylidenecytidine 362-42-5 with stock

Synonyms: 2',3'-O-isopropylidene cytidine; 2',3'-isopropylidenecytidine; 2',3'-O-(1-Methylethylidene)cytidine; 2',3'-O-isopropylidene cytidine; Cytidine, 2',3'-O-(1-methylethylidene)-；

Molecular Formula: C₁₂H₁₇N₃O₅

Molecular Weight: 283.28

CAS Number：362-42-5

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Assay (HPLC),%	≥98.0%
Loss on drying,%	≤1.0%
Residue on ignition,%	≤0.10%

Characteristics: It is white to off-white crystalline powder. It is easily soluble in water and slightly soluble in methanol.

2',3'-O-isopropylidene cytidine(Cas 362-42-5) Usage

Monupivir (Molnupiravir) is a broad-spectrum anti-RNA virus drug, which has obvious effect on novel coronavirus (COVID-19)，significant inhibitory effect on the proliferation of SARS-CoV-2 virus. It is the first oral anti-novel coronavirus drug in the world, which can reduce the risk of hospitalization or death by 50% of COVID-19 patients. 2 ′, 3 ′ -O-isoisopropyl cytidine is an important intermediate in Molnupiravir synthesis.

Storage: Store in a tightly closed container. Maintain in a cool and dry area.

Package: 25kg/drum or as required by customer.

Expiration Date: 2 years

362-42-5 Relevant articles

The first silicon(iv) phthalocyanine-nucleoside conjugates with high photodynamic activity

Shen, Xiao-Min,Zheng, Bi-Yuan,Huang, Xiu-Rong,Wang, Lei,Huang, Jian-Dong

, p. 10398 - 10403 (2013)

A series of novel silicon(iv) phthalocya...

-

Ziff,Fresco

, p. 7338 (1968)

Reactions Between Ribonucleoside Derivatives and Formaldehyde in Ethanol Solution

Bridson, Peter K.,Jiricny, Josef,Kemal, Oeznur,Reese, Colin B.

, p. 208 - 209 (1980)

2',3'-O-Isopropylidene-adenosine, -cytid...

-

Scheit

, p. 113 (1967)

Preparation method of monabiravir

-

Paragraph 0047; 0055-0057; 0062-0064, (2022/01/12)

The preparation method of monabiravir in...

Conversion of: N- acyl amidines to amidoximes: A convenient synthetic approach to molnupiravir (EIDD-2801) from ribose

Ahmed, Ajaz,Ahmed, Qazi Naveed,Mukherjee, Debaraj

, p. 36143 - 36147 (2021/12/04)

An efficient method is described for the...

Nucleotide analogue as well as preparation method and application thereof

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Paragraph 0082-0085, (2021/12/07)

The invention provides a compound having...

Compositions and Methods for Reverse Automated Nucleic Acid Synthesis

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Paragraph 0104-0105, (2019/10/29)

Methods for reverse automated nucleic ac...

362-42-5 Process route

: 67-56-1
methanol

: 77787-58-7
N⁴-benzoyl-2',3'-O-isopropylidene-O²,5'-cyclocytidine

: 362-42-5
2',3'-O-isopropylidenecytidine

: 77772-59-9
1-(2',3'-O-isopropylidene-β-D-ribofuranosyl)-4-methoxy-2-pyrimidinone

: 55-21-0,27208-38-4
benzamide

Conditions

Conditions	Yield
for 5h; Heating;	33% 36% 23%

: C₂₀H₂₉N₃O₇

: 362-42-5
2',3'-O-isopropylidenecytidine

: 2346620-55-9
molnupiravir acetonide